While hyperpigmentation it is one of the most common skin conditions, it can be difficult to treat. It affects women and men of all ethnic groups.Hyperpigmentation is the result of overactive melanocytes, the cells responsible for producing melanin. Melanin is responsible for skin color.
There are three types of hyperpigmentation:
- Post-inflammatory hyperpigmentation-
This type of hyperpigmentation usually follows skin injury, such as, acne injuries, psoriasis, burns, manual friction or chemical peels. If injury is not repeated, it will begin to fade as the skin renews itself - this process could take months or more. Post-inflammatory hyperpigmentation is most common in people with darker skin tones.
Recognized as liver spots or age spots. Lentigines usually come more widespread with age. While 90% of light-skinned people over the age of 60 - their lentigines are not caused by the aging process, but connected to ultra violet radiation exposure.
Very difficult condition to treat. It affects about five to six million women in the United States. A patchy brown discoloration that occurs on sun-exposed areas of the face and is frequently referred to as the “mask of pregnancy” because it often happens during pregnancy. Melasma can materialize in anyone, the disorder is more common in dark skin. Women who are pregnant or women taking estrogen supplements or birth control pills are prone to melasma
- In addition, some illnesses could cause hyperpigmentation. Certain prescription medications make the skin photosensitive, resulting in of hyperpigmentation.
The melanin produced during an inflammatory injury can enter the dermis. These cells can stay in the upper dermis for a long period.
Sun exposure is a common cause of hyperpigmentation. Anyone considering undergoing hyperpigmentation correction should be aware and understand the application of sunscreen is vital. Reapply it as well throughout the day, when going in and out of direct sunlight.
Sun exposure can trigger melisma. Most common treatments for melisma is sun protection. That means applying sunscreen every two hours and wearing a wide-brimmed hat for extra protection, according to dermatologist’s recommendations.
Hormonal in balance can also trigger melisma. Pregnancy (pregnancy mask), or thyroid dysfunction, taking birth control and hormone replacement are possible triggers.
Melanin suppressants sends signature to the cells that produce color to reproduce at a normal rate. Because of the normalize of the melanin process, it will and does take time. It takes generations of “parent cells” to produce children that finally look normal.
This study evaluated the effects of a manganese peptide complex in the treatment of various signs of cutaneous facial photodamage. Individuals used a facial serum formulation containing the manganese peptide complex Manganese Tripeptide-1 twice a day for up to 12 weeks.
At the end of the treatment period, the individuals and a blinded investigator noted improvement in the appearance of several signs of cutaneous photodamage. Predominant among the parameters showing improvement were those associated with hyperpigmentation. In general, at the end of 12 weeks of treatment, photodamage ranking moved from moderate to mild. Treatment was well tolerated with no significant cutaneous inflammation induced by the manganese peptide complex.
- Kojic Acid
- Bellis Perennis (Daisy) Flower Extract
- Azelaic Acid
- (Licorice) Root Extract
- Lactic Acid
- Ascorbic Acid
- Canina (Rose Hip)
- Lycium Barbarum (Goji Berry) Extract
- Octadecenedioic Acid